what to do. Hormonal issues is not restricted to the thyroid however additionally steroid hormones like estrogen make contributions to weight advantage both in males and females. Fat cells are dwelling tissues which behave like endocrine glands or ductless glands and have a tendency to release extra estrogen that growth the chance of weight advantage. Estrogens(especially estradiol) are also made in fat cells in which they purpose greater fats to be stored creating a vicious cycle. This occurs greater .